Early Clinical Treatment of Infant Port-Wine Stains with Multiple Kinds of Laser

Objective To evaluate the efficacy and safety to treat infant port-wine stains( PWS) jointly with intense pulsed light,optimal pulse technology( OPT),pulsed dye lasers( PDL) and continuous output Nd ∶ YAG laser.Methods A retrospective review was performed on 32 infants with PWS who visited the Laser Center of The Second Affiliated Hospital of Medical University of Guangzhou and accepted the treatment of OPT and PDL. Meanwhile,5 of them with verrucous hyperplasia were given the treatment of continuous output Nd ∶ YAG laser. The therapeutic effects were analyzed,and the adverse effects observed.Results All the 32 infants with PWS received 5 consecutive treatments of OPT and PDL at 2-3 month intervals. The cure rate and total effective rate after five treatments were 28. 1% and 84. 4% respectively. Five infants with verrucous hyperplasia were cured after being treated once with continuous output Nd ∶ YAG laser. The effective rate to treat PWS with OPT and PDL was higher than only with PDL.Hypopigmentation and hyperpigmentation were found in 9. 38% and 6. 25% of 32 patients respectively. No superficial scar was observed.Conclusions OPT,PDL and continuous output Nd ∶ YAG laser is effective and safe in terms of early clinical treatment of infant PWS.