Transrectal ultrasound guided systematic 13 core prostate biopsy for diagnosing prostate carcinoma

Objective To evaluate the clinical value of transrectal ultrasound guided systematic 13 core prostate biopsy. Methods A total of 255 patients referred to abnormal digital rectal examination and/or prostate specific antigen 4ng/ml or greater underwent transrectal ultrasound guided systematic 13 core prostate biopsy. That was,in addition to standard sextant biopsies, cores were taken from the far lateral and middle regions of the gland as described by Eskew. Pathological findings of the additional regions were compared with those of the sextant regions.Results Of the patients 28% had cancer on biopsy (71/255).Of the 71patients with prostate cancer 15(21%)had carcinoma only in the additional regions, which would have remained undetected had the sextant biopsy technique been used alone (P0.05).No one of severe complications could be found among the patients who underwent transrectal ultrasound guided systematic 13 core prostate biopsy.Conclusion Our data demonstrated that transrectal ultrasound guided systematic 13 core prostate biopsy can increase the detection rate significantly. It is safe and efficacious, and should be recommended to be used in clinic.