2013•Journal of clinical and experimental medicineRequires access

Study on risk factors for liver metastasis after radical resection of colon cancer

He-li Yuan

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Abstract

Objective To explore the risk factors for liver metastasis after radical resection of colon cancer. Methods The clinical pathological data and situation of postoperative follow-up of 306 patients with colon cancer were retrospectively analyzed. Results The incidence of liver metastasis from colon cancer was 23. 5%( 72 /306). Univariate analysis showed that age,histological differentiation,gross type,vascular invasion,lymph node metastasis,number of lymph nodes dissected,preoperative serum level of CEA and operating time were relevant to liver metastasis( P 0. 05). Logistic regression analysis showed that histological differentiation,vascular invasion and lymph node metastasis were correlated with liver metastasis( P 0. 05). Conclusion Patients with poorly differentiated colon canceer,vascular invasion or lymph node metastasis have higher chance of liver metastasis after radical resection of colon cancer.

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Objective To explore the risk factors for liver metastasis after radical resection of colon cancer. Methods The clinical pathological data and situation of postoperative follow-up of 306 patients with colon cancer were retrospectively analyzed. Results The incidence of liver metastasis from colon cancer was 23. 5%( 72 /306). Univariate analysis showed that age,histological differentiation,gross type,vascular invasion,lymph node metastasis,number of lymph nodes dissected,preoperative serum level of CEA and operating time were relevant to liver metastasis( P 0. 05). Logistic regression analysis showed that histological differentiation,vascular invasion and lymph node metastasis were correlated with liver metastasis( P 0. 05). Conclusion Patients with poorly differentiated colon canceer,vascular invasion or lymph node metastasis have higher chance of liver metastasis after radical resection of colon cancer.

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Available abstract

Objective To explore the risk factors for liver metastasis after radical resection of colon cancer. Methods The clinical pathological data and situation of postoperative follow-up of 306 patients with colon cancer were retrospectively analyzed. Results The incidence of liver metastasis from colon cancer was 23. 5%( 72 /306). Univariate analysis showed that age,histological differentiation,gross type,vascular invasion,lymph node metastasis,number of lymph nodes dissected,preoperative serum level of CEA and operating time were relevant to liver metastasis( P 0. 05). Logistic regression analysis showed that histological differentiation,vascular invasion and lymph node metastasis were correlated with liver metastasis( P 0. 05). Conclusion Patients with poorly differentiated colon canceer,vascular invasion or lymph node metastasis have higher chance of liver metastasis after radical resection of colon cancer.

Key concepts: Medicine, Colorectal cancer, Metastasis, Pathological, Univariate analysis, Lymph node metastasis, Lymph, Oncology

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