Effects of Different Anesthetic Drugs on Cognitive Function of Elderly Patients with Lung Cancer after Operation

Objective To investigate the effects of propofol and sevoflurane on cognitive function of elderly patients with lung cancer after operation. Methods 64 cases of lung cancer patients underwent surgical operation were randomly divided into the propofol group and the sevoflurane group,32 patients in each group. The propofol group and sevoflurane group used propofol and sevoflurane for general anesthesia,respectively. Spontaneous breathing recovery time,called the open time and recovery time were recorded,and cognitive function and pain were evaluated by mini-mental state examination( MMSE) and visual analogue score( VAS). Results Breathing recovery time,called the open time and recovery time of orientation between the propofol group and sevoflurane group had statistical difference,P 0. 05; postoperative and preoperative 6 h,12 h and 24 h MMSE score in the propofol group had statistical difference,P 0. 05; postoperative and preoperative 6 h,12 h,24 h and 3 d MMSE score in the sevoflurane group had statistical difference,P 0. 05; postoperative 6 h and 12 h MMSE score between the propofol group and sevoflurane group had statistical difference,P 0. 05. Conclusion Effect of propofol on the cognitive function of postoperative elderly patients with lung cancer is slight,and it has faster postoperative recovery.