Hepatitis infection in newly admitted students of a vocational college in Guangdong province

Objective To investigate the infection rate of HBV in entrant students and evaluate the effectiveness of hepatitis B vaccine. Methods The five markers of HBV in 2867 serum specimens were detected by ELISA. The information of HBV vaccine injection was collected through questionnaire. Results The positive rate of HBsAg in 2876 students was 4.62% and the serum HBsAg positive rates in male was higher than female(P0.05). Among the five patterns of HBsAg+, the HBsAg+/HBeAg+/HBcAb+ occupied 31.58% and HBsAg+/HBeAb+/HBcAb+ occupied 51.13%. The vaccination rate of male and female was 61.99% and 60.12% respectively in 1756 vaccinated students and there was no statistics difference in gender. The positive rate of HBsAb was 30.32% in the students in total, and was 49.66% in the vaccinated students. Conclusion The resistance to HBV of entrant students was rather low, therefore, it is necessary for them to receive HBV vaccine. Health education should also be promoted to prevent the transmission in campus.