Protection against radiation by dehydroepiandrosterone,androstenediol,and androstenetriol
Wen Su
Abstract
Wen Su
Abstract
Dehydroepiandrosterone(DHEA)was considered to be a biologically irrelevant interme-diate in the pathway of steroid hormones.DHEA provides one of the first avenues by which the im-mune system can be globally regulated to increase resistance to a variety of lethal infections.The downstream metabolites of DHEA particularly androstenediol(AED)and androstenetriol(AET)were sig-nificantly more efficacious at preventing morbidity and mortality associated with viral and bacterial in-fection.
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Dehydroepiandrosterone(DHEA)was considered to be a biologically irrelevant interme-diate in the pathway of steroid hormones.DHEA provides one of the first avenues by which the im-mune system can be globally regulated to increase resistance to a variety of lethal infections.The downstream metabolites of DHEA particularly androstenediol(AED)and androstenetriol(AET)were sig-nificantly more efficacious at preventing morbidity and mortality associated with viral and bacterial in-fection.
Key concepts: Androstenediol, Dehydroepiandrosterone, Hormone, Biology, Medicine, Internal medicine, Endocrinology, Androgen