The Clinical Study on Preventing Radioactive Esophagitis in Patients with Lung Cancer

Objective: To study the preventive effect of the anti-inflammatory dehydrating agent (80,000 units gentamycin taken orally 2 times a day, 4 mg Dexamethasone needle taken orally 3 times a day; orallly taking of 20 mL 20 % mannitol 3 times a daily) and Omeprazole on patients with radioactive esophagitis. Secondary to lung cancer . Methods: In this randomized,double-blind study, 100 patients were allocated to treatment group (50 cases), received the anti-inflammatory dehydrating agent and 20 mg Omeprazole , one time a day , from the first day of radioactive treatment. Treatment course was two weeks .control group 50 cases; only received radiotherapy. The incidence of radioactive esophagitis. Secondary to lung cancer was compared between the two groups.Results: The treatment group was 4.00 % , the control group was 20.00 , there was a significant difference (P0.05). Conclusions: the anti-inflammatory dehydrating agent and Omeprazole has the effective on preventing radioactive esophagitis. Secondary to lung cancer.