The application of total inhalational anesthesia with sevoflurane for cleft lip repair in infants

Objective To compare the feasibility and safety between total inhalation anesthesia with sevoflurane l and propofol-fentanyl intravenous anesthesia in cleft lip repair in infants.MethodsSixty cleft lip infants with ASA Ⅰgrade were randomly divided into group S(sevoflurane group,n=30)and group P(propofol-fentanyl group,n=30).MAP and HR before anesthesia induction,during endotrachea intubation and incision,30 min after the beginning of operation were recorded respectively.The extubation time,the time when modified Aldrete score reached to 9,the dosage of vecuronium,and the incidence of agitation and vomiting were also recorded.ResultsHR in group S was more stable than that in group P during tracheal intubation.The extubation time and the time when modified Aldrete score reached to 9 in group S were significantly decreased.(P0.01).The incidence of agitation in group S was higher than that in group P(P0.01).There was no statistical significance in the incidence of vomiting between the two groups.The dosage of vecuronium in group S was lower than that in group P(P0.01).ConclusionTotal inhalational anesthesia with sevoflurane is a steady anesthesia method for infant cleft lip repair with quick recovery but a high incidence of agitation.