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[Effect of preparation on the major chemical constituents of Polygonum multiflorum].

Zhiguo Zhang, Tai-sheng Lü, Qingqiang Yao

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Abstract

OBJECTIVE: To study the dynamic changes of Emodin, Physcion, Emodin-8-O-beta-D-glucopyranoside, Physcion-8-O-beta-D-glucopyranoside and 2,3,5,4'-tetrahydtoxysilbene-2-O-beta-D-glucopyranoside in Polygonum multiflorum during preparation and analyze their changing laws. METHODS: Five major constituents before and after preparation were determined by RP-HPLC methods. RESULTS: The five ingredients decreased significantly after preparation. CONCLUSION: The major chemical constituents of Polygonum multiflorum decrease significantly, suggesting the necessarity of prepared Polygonum multiflorum in clinical application worth studying.

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What this paper is about

OBJECTIVE: To study the dynamic changes of Emodin, Physcion, Emodin-8-O-beta-D-glucopyranoside, Physcion-8-O-beta-D-glucopyranoside and 2,3,5,4'-tetrahydtoxysilbene-2-O-beta-D-glucopyranoside in Polygonum multiflorum during preparation and analyze their changing laws. METHODS: Five major constituents before and after preparation were determined by RP-HPLC methods. RESULTS: The five ingredients decreased significantly after preparation. CONCLUSION: The major chemical constituents of Polygonum multiflorum decrease significantly, suggesting the necessarity of prepared Polygonum multiflorum in clinical application worth studying.

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Available abstract

OBJECTIVE: To study the dynamic changes of Emodin, Physcion, Emodin-8-O-beta-D-glucopyranoside, Physcion-8-O-beta-D-glucopyranoside and 2,3,5,4'-tetrahydtoxysilbene-2-O-beta-D-glucopyranoside in Polygonum multiflorum during preparation and analyze their changing laws. METHODS: Five major constituents before and after preparation were determined by RP-HPLC methods. RESULTS: The five ingredients decreased significantly after preparation. CONCLUSION: The major chemical constituents of Polygonum multiflorum decrease significantly, suggesting the necessarity of prepared Polygonum multiflorum in clinical application worth studying.

Key concepts: Polygonum, Emodin, Chemistry, Chemical constituents, Chromatography, High-performance liquid chromatography, Traditional medicine, Medicine

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