2013•Basic & Clinical MedicineRequires access
Cholesterol metabolism of macrophage foam cells and atherosclerosis
Xiaoshu Cheng
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Abstract
Foam cells is formed in early stage of atherosclerosis.The transformation of macrophage foam cell involves the disruption of a homeostatic mechanism that controls the uptake,intracellular metabolism and efflux of cholesterol by macrophages.The research of the mechanism of foam cells has a great significance for the prevention and the treatment for the atherosclerosis.