2005•Chinese New Drugs JournalRequires access

Advances in research of betulinic acids

Jinhui Wu

Abstract

Betulinic acids are a kind of natural product with anti-HIV-1 virus and anti-tumor activity extractable from a lot of plants. They include betulinic acid,23-hydroxy betulinic acid, betulin, and others. Nowaday a large quantity of betulinic acid derivatives with biological activity has been synthesized by structure modification. In this paper, the research advances in this field are reviewed.

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Key concepts: Betulinic acid, Betulin, Chemistry, Natural product, Organic chemistry, Biology, Genetics