2006Shenyang Yaoke Daxue xuebaoRequires access

Chemical constituents of Callicarpa macrophylla Vahl.

Sun Qi-shi

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Abstract

Objective To study the chemical constituents from Callicarpa macrophylla Vahl.Methods The compounds were isolated by column chromatography on silica gel,Sephadex LH-20 and purified by recrystallization.Their structures were determined on the basis of physicochemical properties and spectroscopic evidence.Results Six compounds were isolated and identified as α-amyrin(1),ursolic acid(2),2α,3α,19α-trihydroxyurs-12-en-28-oic acid(3),betulinic acid(4),β-sitosterol(5),daucosterol(6).Conclusions Compounds 1 and 3 are obtained from this plant for the first time.

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What this paper is about

Objective To study the chemical constituents from Callicarpa macrophylla Vahl.Methods The compounds were isolated by column chromatography on silica gel,Sephadex LH-20 and purified by recrystallization.Their structures were determined on the basis of physicochemical properties and spectroscopic evidence.Results Six compounds were isolated and identified as α-amyrin(1),ursolic acid(2),2α,3α,19α-trihydroxyurs-12-en-28-oic acid(3),betulinic acid(4),β-sitosterol(5),daucosterol(6).Conclusions Compounds 1 and 3 are obtained from this plant for the first time.

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Available abstract

Objective To study the chemical constituents from Callicarpa macrophylla Vahl.Methods The compounds were isolated by column chromatography on silica gel,Sephadex LH-20 and purified by recrystallization.Their structures were determined on the basis of physicochemical properties and spectroscopic evidence.Results Six compounds were isolated and identified as α-amyrin(1),ursolic acid(2),2α,3α,19α-trihydroxyurs-12-en-28-oic acid(3),betulinic acid(4),β-sitosterol(5),daucosterol(6).Conclusions Compounds 1 and 3 are obtained from this plant for the first time.

Key concepts: Daucosterol, Ursolic acid, Betulinic acid, Chemical constituents, Chemistry, Sephadex, Silica gel, Column chromatography

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