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The Effect Analysis of Omeprazole in Helicobacter Pylori-positive Duodenal Ulcer Treatment

HE Xiangyu

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Abstract

Objective To observe the effect of omeprazole in helicobacter pylori-positive duodenal ulcer treatment.Methods 40 patients with helicobacter pylori-positive duodenal ulcer were equally divided into two groups,the treatment group received omeprazole-based triple therapy,the control group received esomeprazole-based triple therapy.Results After the treatment,the total effective rate was 95.0% in the treatment group,the total effective rate was 75.0% in the control group,the clinical efficacy of the treatment group was significantly better than the control group(P 0.05).Hp eradication rate was 90.0% and 75.0% in the treatment group and the control group,the statistical analysis showed that the eradication rate in the treatment group was significantly better than the control group(P 0.05).There was no significant difference in adverse reactions of two groups(P 0.05).Conclusion Omeprazole in helicobacter pylori-positive duodenal ulcer treatment has good effect,more safet in Hp eradication rate,which is worthy of wide application.

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What this paper is about

Objective To observe the effect of omeprazole in helicobacter pylori-positive duodenal ulcer treatment.Methods 40 patients with helicobacter pylori-positive duodenal ulcer were equally divided into two groups,the treatment group received omeprazole-based triple therapy,the control group received esomeprazole-based triple therapy.Results After the treatment,the total effective rate was 95.0% in the treatment group,the total effective rate was 75.0% in the control group,the clinical efficacy of the treatment group was significantly better than the control group(P 0.05).Hp eradication rate was 90.0% and 75.0% in the treatment group and the control group,the statistical analysis showed that the eradication rate in the treatment group was significantly better than the control group(P 0.05).There was no significant difference in adverse reactions of two groups(P 0.05).Conclusion Omeprazole in helicobacter pylori-positive duodenal ulcer treatment has good effect,more safet in Hp eradication rate,which is worthy of wide application.

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Available abstract

Objective To observe the effect of omeprazole in helicobacter pylori-positive duodenal ulcer treatment.Methods 40 patients with helicobacter pylori-positive duodenal ulcer were equally divided into two groups,the treatment group received omeprazole-based triple therapy,the control group received esomeprazole-based triple therapy.Results After the treatment,the total effective rate was 95.0% in the treatment group,the total effective rate was 75.0% in the control group,the clinical efficacy of the treatment group was significantly better than the control group(P 0.05).Hp eradication rate was 90.0% and 75.0% in the treatment group and the control group,the statistical analysis showed that the eradication rate in the treatment group was significantly better than the control group(P 0.05).There was no significant difference in adverse reactions of two groups(P 0.05).Conclusion Omeprazole in helicobacter pylori-positive duodenal ulcer treatment has good effect,more safet in Hp eradication rate,which is worthy of wide application.

Key concepts: Omeprazole, Medicine, Helicobacter pylori, Gastroenterology, Internal medicine, Esomeprazole, Duodenal ulcer, Helicobacter

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