The Study on the Determination of Glomerular Filtration Rate of Chronic Renal Insufficiency with Renal Dynamic Imaging

Objective To investigate the clinical applications of renal dynamic imaging to measure chronic renal insufficiency disease glomerular filtration rate. Methods 72 patients with chronic renal insufficiency were randomly divided into experiment group and control group, 36 cases in each group. In the experiment group 99mTc-DTPA renal dynamic imaging was used to detect the GFR, while in the control group BUN, Scr and Ccr were detected. The relativity of GFR and BUN、Scr and Ccr, the difference of GFR value and Ccr value of mean of the two groups were compared and analyzed. Results The GFR value of the experiment group was significantly lower than Ccr value, the difference was statistically significant (P0.05). Relevant analysis showed there was a positive correlation (r=0.712) between GFR and Scr, a negative correlation (r=-0.624) between GFR and Ccr and there was no significant correlation (r=-0.118) between GFR and BUN. These indicated that before and after treatment, the GFR level of the chronic renal insufficiency patients did not change significantly and the GFR level difference was not statistically significant (P0.05). Conclusion Renal dynamic imaging method is simple and sensitive, and can be used for the determination of renal function of chronic renal insufficiency, which has important clinical value for making treatment options and prognosis.