Sero-epidemiological survey of hepatitis B virus infection in different populations in Hainan Province.

Objective To understand the current infection status of hepatitis B virus in Hainan Province and evaluate the effects of use of hepatitis B vaccine in children since 1992.Methods Questionaire survey of infectious status of hepatitis B virus in diffetent populaitons aged 1-59 years was made and veinous blood samples were meatime randomly collected and assayed by National CDC. Results The prevalent rate of HBV was 40.8% and the HBsAg positive rate was 8.4%,which dropped by 43.6% and 9.4 % as compared with that of 1992.The full course of Hepatitis B vaccination rate in children aged 1-4 years and 5-14 years children were 97.3% and 65.4%.While the vaccination rate was84.0% and 41.1%.HBV infection rate was 3.7% and 20.6%,HBsAg carrying rate was 1.1% and 4.04%.The HBV prevalence and HBsAg carrying rate was 65.9% and 13.5% in population of 15-59 years old.The Hepatitis B vaccination rate and in time rate of rural populations were significantly higher than urban ones except the 1-4 year group,he HBV prevalence rate and HBsAg positive rate were significantly lower than urban ones.The infection rate of HBV and HBsAg positive rates in workers and peasants were significantly higher than others,and descending along with the iincrease of educational levels The Familial Clustering of HBV Infection was founded(about44.1%). Conclusion Hepatitis B virus infection was effectively controlled after application of hepatitis B vaccine freely,the infection rate,HBsAg carrying rate and timely vaccination rate in children under 15 yeats old are greatly increased.