Clinical Study of Propofol Combined with Ketamine Aided Sacral Anesthesia in Children

Objective:To compare the clinical effects of propofol combined with ketamine and sacral anesthesia adided ketamine combinted with propofol in children.Methods: Sixty-two pediatric patients(6 years and 3 monthes)who undergoing elective operations below belly were randomly allocated to either a conventional anesthesia group(propofol combined with ketamine,group Ⅰ组) or sacral anesthesia aided ketamine combined with propofol(group Ⅱ组).The variation of peri-anesthesia blood pressure(SBP and DBP),heart rate(HR),respiration rate(R R),pulse oxygen saturation(SpO2)were tested and recorded the wake time,the peri-operative incidence of restressness and vomit were observed.Results: The post-anesthesia SBP and DBP(P0.01),HR(P0.01),RR(P0.05) in groupⅠ were significantly increased than its pre-anesthesia level the wake time,peri-operative incidence of restlessness and vomit in groupⅡ were remarkably shorter or lower than those in groupⅠ(P0.01).Conclusion:With stable respiration and circulation maintenance,shorter wake time,peri-operative incidence of restlessness and vomit in group Ⅱ has clinical effect than in group Ⅰ.