2013Chinese journal of integrated traditional and Western medicineRequires access

The expression and clinical significance of proto-oncogene Pokemon in peripheral blood of hepatocellular carcinoma patients

Gao Z

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Abstract

Objective: To investigate the expression and clinical significance of proto-oncogene Pokemon in serum of patients with hepatocellular carcinoma.Methods: The expression of Pokemon in 84 cases of hepatocellular carcinoma,40 cases of hepatic cirrhosis and 20 cases of healthy controls were detected by enzyme-linked immunosorbent assay(ELISA).Results: The serum level of Pokemon in HCC was higher than these in the hepatic cirrhosis and healthy people(P 0.05).The expression of Pokemon was closely related to the size of tumor and distant metastasis,but no correlation with AFP.Conclusion: Pokemon may become a new effective marker in the diagnosis of HCC,meanwhile the expression level of Pokemon may be useful to predict the size of tumor and distant metastasis.

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Objective: To investigate the expression and clinical significance of proto-oncogene Pokemon in serum of patients with hepatocellular carcinoma.Methods: The expression of Pokemon in 84 cases of hepatocellular carcinoma,40 cases of hepatic cirrhosis and 20 cases of healthy controls were detected by enzyme-linked immunosorbent assay(ELISA).Results: The serum level of Pokemon in HCC was higher than these in the hepatic cirrhosis and healthy people(P 0.05).The expression of Pokemon was closely related to the size of tumor and distant metastasis,but no correlation with AFP.Conclusion: Pokemon may become a new effective marker in the diagnosis of HCC,meanwhile the expression level of Pokemon may be useful to predict the size of tumor and distant metastasis.

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Available abstract

Objective: To investigate the expression and clinical significance of proto-oncogene Pokemon in serum of patients with hepatocellular carcinoma.Methods: The expression of Pokemon in 84 cases of hepatocellular carcinoma,40 cases of hepatic cirrhosis and 20 cases of healthy controls were detected by enzyme-linked immunosorbent assay(ELISA).Results: The serum level of Pokemon in HCC was higher than these in the hepatic cirrhosis and healthy people(P 0.05).The expression of Pokemon was closely related to the size of tumor and distant metastasis,but no correlation with AFP.Conclusion: Pokemon may become a new effective marker in the diagnosis of HCC,meanwhile the expression level of Pokemon may be useful to predict the size of tumor and distant metastasis.

Key concepts: Hepatocellular carcinoma, Cirrhosis, Oncogene, Medicine, Clinical significance, Distant metastasis, Peripheral blood, Metastasis

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