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2009•Zhongguo fuyou baojianRequires access

Application of ultrasound-guided transabdominal chorionic villus sampling in the prenatal diagnosis

Min Li

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Abstract

Objective:To evaluate the feasibility and safety of prenatal diagnosis of thalassemia by Transabdominal chorionic villus sampling(TA-CVS) via the guidance of Ultrasound in fierst trimester of gestation.Methods:72 cases singleton pregnancies at Thalassemia high risk were referred from January 2005 to June 2007.Results:TA-CVS was performed in the 11-13 gestation weeks.The success rate at the first attempt was 98.6%.Post CVS spontaneous fetal loss rate was 1.40%.The intrauterine infection was 0.Conclusion:TA-CVS appears safe and feasible and can be offered in the prenatal diagnosis of thalassemia in fierst trimester of gestation.

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What this paper is about

Objective:To evaluate the feasibility and safety of prenatal diagnosis of thalassemia by Transabdominal chorionic villus sampling(TA-CVS) via the guidance of Ultrasound in fierst trimester of gestation.Methods:72 cases singleton pregnancies at Thalassemia high risk were referred from January 2005 to June 2007.Results:TA-CVS was performed in the 11-13 gestation weeks.The success rate at the first attempt was 98.6%.Post CVS spontaneous fetal loss rate was 1.40%.The intrauterine infection was 0.Conclusion:TA-CVS appears safe and feasible and can be offered in the prenatal diagnosis of thalassemia in fierst trimester of gestation.

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Available abstract

Objective:To evaluate the feasibility and safety of prenatal diagnosis of thalassemia by Transabdominal chorionic villus sampling(TA-CVS) via the guidance of Ultrasound in fierst trimester of gestation.Methods:72 cases singleton pregnancies at Thalassemia high risk were referred from January 2005 to June 2007.Results:TA-CVS was performed in the 11-13 gestation weeks.The success rate at the first attempt was 98.6%.Post CVS spontaneous fetal loss rate was 1.40%.The intrauterine infection was 0.Conclusion:TA-CVS appears safe and feasible and can be offered in the prenatal diagnosis of thalassemia in fierst trimester of gestation.

Key concepts: Chorionic villus sampling, Medicine, Obstetrics, Gestation, Prenatal diagnosis, Thalassemia, Fetus, Pregnancy

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