2009•Unpublished venueRequires access

Clinical observation of sevoflurane and remifentanil used for anesthesia in children of outpatient surgery

Feng Xing

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Abstract

objective:To evaluate the clinical benefit of sevoflurane and remifentanil for children of outpatient surgery.METHODS:Forty American Society of Anestllesiologiests physical status(ASA)I or II children aged1—3years were randomlydivided into two groups.30 in each group.Group A:ketamine,Group B:sevoflurane+remifentanil group.Induction of anesthesia,children in group A received ketamine(6-8mg/kg) by intramuscular injection,and then received ketamine 1-1.2mg/(kg·h)during [JP3]the maintenance of operation.In group B,anesthesia was induced by inhalation of sevoflurane and remifentanil0.5ug/(kg。min)intravenously,was maintained with remifentanil 0.10-0.25ug/(kg·min)and sevoflurane at 1-1.5 minimumalveolar concentration(MAC).We adjusted the depth of anesthesia according to the change of hemodynamics.Results:HR increased(P0.01) and MAP increased(P0.05) in group A,and HR kept in faster range compared with that in group B(P0.05).In group B,Hemodynamics Was stable throughout the operation.In group B the time to awake Was earlier than that in group A(P0.01),but the incidence of agitation Was significantly higher.CONCLUSION:Sevoflurane and remifentanil Can ofer superior stable and comfortable operation in children.

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objective:To evaluate the clinical benefit of sevoflurane and remifentanil for children of outpatient surgery.METHODS:Forty American Society of Anestllesiologiests physical status(ASA)I or II children aged1—3years were randomlydivided into two groups.30 in each group.Group A:ketamine,Group B:sevoflurane+remifentanil group.Induction of anesthesia,children in group A received ketamine(6-8mg/kg) by intramuscular injection,and then received ketamine 1-1.2mg/(kg·h)during [JP3]the maintenance of operation.In group B,anesthesia was induced by inhalation of sevoflurane and remifentanil0.5ug/(kg。min)intravenously,was maintained with remifentanil 0.10-0.25ug/(kg·min)and sevoflurane at 1-1.5 minimumalveolar concentration(MAC).We adjusted the depth of anesthesia according to the change of hemodynamics.Results:HR increased(P0.01) and MAP increased(P0.05) in group A,and HR kept in faster range compared with that in group B(P0.05).In group B,Hemodynamics Was stable throughout the operation.In group B the time to awake Was earlier than that in group A(P0.01),but the incidence of agitation Was significantly higher.CONCLUSION:Sevoflurane and remifentanil Can ofer superior stable and comfortable operation in children.

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Available abstract

objective:To evaluate the clinical benefit of sevoflurane and remifentanil for children of outpatient surgery.METHODS:Forty American Society of Anestllesiologiests physical status(ASA)I or II children aged1—3years were randomlydivided into two groups.30 in each group.Group A:ketamine,Group B:sevoflurane+remifentanil group.Induction of anesthesia,children in group A received ketamine(6-8mg/kg) by intramuscular injection,and then received ketamine 1-1.2mg/(kg·h)during [JP3]the maintenance of operation.In group B,anesthesia was induced by inhalation of sevoflurane and remifentanil0.5ug/(kg。min)intravenously,was maintained with remifentanil 0.10-0.25ug/(kg·min)and sevoflurane at 1-1.5 minimumalveolar concentration(MAC).We adjusted the depth of anesthesia according to the change of hemodynamics.Results:HR increased(P0.01) and MAP increased(P0.05) in group A,and HR kept in faster range compared with that in group B(P0.05).In group B,Hemodynamics Was stable throughout the operation.In group B the time to awake Was earlier than that in group A(P0.01),but the incidence of agitation Was significantly higher.CONCLUSION:Sevoflurane and remifentanil Can ofer superior stable and comfortable operation in children.

Key concepts: Remifentanil, Sevoflurane, Medicine, Anesthesia, Ketamine, Hemodynamics, Outpatient surgery, Group B

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