Jin Zheng
Abstract
Ethyl R-2-hydroxy popionate reacted with thionyl chloride to produce ethyl S-2-chloropopionate,with yield of 95.0% and purity 99.0%.The synthetic influence in reactant mole ratio,the reaction temperature and time were discussed by orthogonal test.The product structure was characterized by IR spectra,1H NMR and ESI-MS.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Ethyl R-2-hydroxy popionate reacted with thionyl chloride to produce ethyl S-2-chloropopionate,with yield of 95.0% and purity 99.0%.The synthetic influence in reactant mole ratio,the reaction temperature and time were discussed by orthogonal test.The product structure was characterized by IR spectra,1H NMR and ESI-MS.
Key concepts: Thionyl chloride, Yield (engineering), Chemistry, Proton NMR, Nuclear chemistry, Chloride, Organic chemistry, Medicinal chemistry