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Detecting serum sICAM-1 in patients with colorectal carcinoma and early diagnosis

Tian Xiaolin

Abstract

Objective To investigate the relationship between the early diagnosis of colorectal carcinoma and contents of serum sICAM 1. Methods The levels of serum sICAM 1 were determined by ELISA in 60 cases of colorectal carcinoma, 21 gastric carcinoma, 17 breast carcinoma and 9 healthy controls. Results Serum sICAM 1 of colorectal and gastric carcinoma was much higher than that of healthy control (P0 01). Serum sICAM 1 of breast carcinoma was not significantly different from healthy controls (P0 05). Positive rate of serum sICAM 1 in colorectal carcinoma was higher than that in gastric carcinoma (P0 05). Level of serum sICAM 1 was significantly related to the course and pathology of colorectal carcinoma. Conclusion The level of serum sICAM 1 is one of early diagnosis standards in colorectal carcinoma.

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Key concepts: Medicine, Breast carcinoma, Gastric carcinoma, Colorectal cancer, Carcinoma, Internal medicine, Gastroenterology, Oncology