ScholarLens Back to search
2006•Chengde Yixueyuan xuebaoRequires access

THE EXPRESSION AND SIGNIFICANCE OF VASCULAR ENDOTHELIAL GROWTH FACTOR C IN COLORECTAL CARCINOMA

Pang Jiu-ling

Open publisher page 0 citations

Abstract

Objective:To study the expression of vascular endothelial growth factor-C in colorectal carcinoma and its relationship with lymph node metastasis.Methods:The expression of VEGF-C protein in colorectal carcinoma tissues obtained from 80 patients who underwent radical resection was detected by FCM.Results:VEGF-C protein was expressed in 53.8% of patients.Its expression was more frequently detected in tumors with lymph node metastasis than in those without lymph node metastasis(P0.05),and there was significant correlation between its expression and lymphatic invasion, Duke's staging(P0.05).However,there was no significant correlation between its expression and the age,gender,tumor location,inflammation cell invasion.Conclusion:The expression of VEGF-C is closely related to lymph node metastasis,and it is likely to take part in tumor lymphangiogenesis.

About this research paper

What this paper is about

Objective:To study the expression of vascular endothelial growth factor-C in colorectal carcinoma and its relationship with lymph node metastasis.Methods:The expression of VEGF-C protein in colorectal carcinoma tissues obtained from 80 patients who underwent radical resection was detected by FCM.Results:VEGF-C protein was expressed in 53.8% of patients.Its expression was more frequently detected in tumors with lymph node metastasis than in those without lymph node metastasis(P0.05),and there was significant correlation between its expression and lymphatic invasion, Duke's staging(P0.05).However,there was no significant correlation between its expression and the age,gender,tumor location,inflammation cell invasion.Conclusion:The expression of VEGF-C is closely related to lymph node metastasis,and it is likely to take part in tumor lymphangiogenesis.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To study the expression of vascular endothelial growth factor-C in colorectal carcinoma and its relationship with lymph node metastasis.Methods:The expression of VEGF-C protein in colorectal carcinoma tissues obtained from 80 patients who underwent radical resection was detected by FCM.Results:VEGF-C protein was expressed in 53.8% of patients.Its expression was more frequently detected in tumors with lymph node metastasis than in those without lymph node metastasis(P0.05),and there was significant correlation between its expression and lymphatic invasion, Duke's staging(P0.05).However,there was no significant correlation between its expression and the age,gender,tumor location,inflammation cell invasion.Conclusion:The expression of VEGF-C is closely related to lymph node metastasis,and it is likely to take part in tumor lymphangiogenesis.

Key concepts: Lymphangiogenesis, Medicine, Vascular endothelial growth factor C, Lymph node metastasis, Colorectal cancer, Lymph node, Vascular endothelial growth factor, Lymphatic system

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
THE EXPRESSION AND SIGNIFICANCE OF VASCULAR ENDOTHELIAL GROWTH FACTOR C IN COLORECTAL CARCINOMA — Research Paper | ScholarLens