2009•Zhonghua putong waike zazhiRequires access

Clinical application of intraoperative parathyroid hormone assay during parathyroidectomy for secondary hyperparathyroidism

Wenbin Zhou

Abstract

Objective To investigate the application and criteria of intraoperative parathyroid hormone assay during surgery of secondary hyperparathyroidism.Methods Subtotal parathyroidectomy was performed in 17 cases of secondary hyperparathyroidism.Parathyroid hormone assay was performed after induction of anaesthesia but before incision(PTH0) and 10min(PTH10) after subtotal parathyroidectomy.Two successive criteria of PTH decrease were used:(1) PTH10 of ≤150pg/mL;(2) PTH10 /PTH0≤30%.ResultsFifteen cases met the criteria.There were PTH15 pg/m in 4 cases,PTH of 15-65 pg/mL in 6 cases,and PTH of 65-185.2 pg/mL in 5 cases day 7 postoperatively.Bone pain resolved in all cases after operation.ConclusionsIntraoperative parathyroid hormone assay can help for hyperparathyroid gland resection in secondary hyperparathyroidism,and can improve the successful rate of operation

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Key concepts: Medicine, Parathyroidectomy, Parathyroid hormone, Secondary hyperparathyroidism, Hyperparathyroidism, Primary hyperparathyroidism, Bone pain, Surgery