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Research progress in endocrine therapy for breast cancer

Jun Gu

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Abstract

Endocrine therapy is one of the important methods for the treatment of receptor-positive breast cancer,though some receptor-positive patients fail to respond to it,and still others develop acquired endocrine resistance after an initial response.This article outlines the progress in the researches on endocrine therapy response-related factors,application of aromatase inhibitors,mechanisms of endocrine therapy resistance,and strategies to overcome endocrine resistance.

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What this paper is about

Endocrine therapy is one of the important methods for the treatment of receptor-positive breast cancer,though some receptor-positive patients fail to respond to it,and still others develop acquired endocrine resistance after an initial response.This article outlines the progress in the researches on endocrine therapy response-related factors,application of aromatase inhibitors,mechanisms of endocrine therapy resistance,and strategies to overcome endocrine resistance.

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Available abstract

Endocrine therapy is one of the important methods for the treatment of receptor-positive breast cancer,though some receptor-positive patients fail to respond to it,and still others develop acquired endocrine resistance after an initial response.This article outlines the progress in the researches on endocrine therapy response-related factors,application of aromatase inhibitors,mechanisms of endocrine therapy resistance,and strategies to overcome endocrine resistance.

Key concepts: Endocrine system, Aromatase, Breast cancer, Medicine, Cancer, Aromatase inhibitor, Oncology, Internal medicine

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