2003•PubMedRequires access

[Experimental study on effect of the water extract of dogwood fruits on the liver and testis in rats model of kidney-yang deficiency].

Chunsheng Li, Guoxi Zhang, Ti-ren Shi, Xiao-Xia Dong, Pi Chang Sun, Dian-Dong Li, Hong-zhang Xu, Keji Chen

Abstract

OBJECTIVE: To explore the effect of Dogwood fruits on tonifying kidney-yang. METHOD: The effect of the water extract of Dogwood fruits on rats model of kidney-yang deficiency with the hydrocortisone was observed. RESULT: The water extract of Dogwood fruits could make normal the liver weight, and mitigate hepatocyte pathologic changes, increase the heptocellular levels of RNA and hepatin, and decrease the malondialdehyde (MDA) in rats model of kidney-yang deficiency. It could also make the viscera quotiety return to normal way and increase the levels of RNA in the interstitial cells of testicle in rats model of kidney-yang deficiency. CONCLUSION: Water extract of Dogwood fruits can protect and improve the functions of the liver and testicle in rats model of kidney-yang deficiency.

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Key concepts: Kidney, Yang deficiency, Malondialdehyde, Hepatocyte, Internal medicine, Endocrinology, Rat model, Biology