Using TMAD combined with TEI index to evaluate left ventricular systolic function in uremia patients

Objective To determine Tissue Motion Annular Displacement( TMAD) of the mitral valves combined with TEI index to evaluate changes of left ventricular systolic function in patients with uremia. Methods We selected 42 early uremia patients as research objects. Transthoracic conventional two- dimensional echocardiography showed no significant abnormality in cardiac structure and left ventricular systolic function. Analysis were performed on the measurement result of TMAD using STI and TEI index using Doppler( TDI). Another 30 cases were used as a normal control group,and compared to the uremia patient group. Results 2D- STI determination of systolic mitral valve annulus in patients with Ventricular septal( TMAD- S),the displacement of the left ventricle wall( TMAD- L) and the displacement of midpoint of the mitral valve annulus( TMAD- Midpt),and the maximum displacement of the midpoint of the mitral valve annulus as a percentage of left ventricular long- axis( TMAD- Midpt%) were lower than those in the control group; the differences were statistically significant( P 0. 05). The TEI index of case group measured with tissueDoppler Imaging( TDI) was significantly higher than the control group,the difference was statistically significant( P 0. 05). TMAD value of case group was negatively correlated with TEI index( r =- 0. 592,P 0. 05). Conclusion TMAD technology combined with TEI index can find the left ventricular systolic dysfunction earlier than two dimensional echocardiography and provide reliable evidence for early prevention and treatment. It is a practical method.