2010Chinese Journal of PharmaceuticalsRequires access

Progress of Vesicles and Particulates for Transdermal Drug Delivery System

Fanzhu Li

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Abstract

Several methods have been adopted to increase the permeation of drugs in transdermal drug delivery systems in recent years.One simple and convenient approach is the use of vesicles and particulates.This paper provides an overview of the development of vesicles(deformable liposomes,ethosomes,niosomes) and particulates(microemulsions,solid lipid nanoparticles and nanostructured lipid carriers) for transdermal drug delivery system,with special emphasis on the mechanism and research in this fi eld.

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What this paper is about

Several methods have been adopted to increase the permeation of drugs in transdermal drug delivery systems in recent years.One simple and convenient approach is the use of vesicles and particulates.This paper provides an overview of the development of vesicles(deformable liposomes,ethosomes,niosomes) and particulates(microemulsions,solid lipid nanoparticles and nanostructured lipid carriers) for transdermal drug delivery system,with special emphasis on the mechanism and research in this fi eld.

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Available abstract

Several methods have been adopted to increase the permeation of drugs in transdermal drug delivery systems in recent years.One simple and convenient approach is the use of vesicles and particulates.This paper provides an overview of the development of vesicles(deformable liposomes,ethosomes,niosomes) and particulates(microemulsions,solid lipid nanoparticles and nanostructured lipid carriers) for transdermal drug delivery system,with special emphasis on the mechanism and research in this fi eld.

Key concepts: Transdermal, Niosome, Liposome, Chemistry, Vesicle, Drug delivery, Drug, Nanotechnology

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