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Diagnosis value of IGF-1 and CEA in benign and malignant pleural effusion

Li Shen

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Abstract

Objective To investigate the diagnosis value of insulin like growth factor 1(IGF 1) in benign and malignant pleural effusion compared with carcinoembryonic antigen(CEA).Methods IGF 1 and CEA were analyzed by ELISA in 33 cases with benign pleural effusion and 32 cases with malignant pleural effusion.Results The concentration of IGF 1 were significantly higher in malignant pleural effusion(110.20±20.59nmol/L) than that in benign group(76.70±18.95nmol/L),P0.001.IGF 1 was slightly less valuable than CEA in diagnosis of malignant pleural effusion.Conclusion In pleural effusions IGF 1 may be an important indicator to help to differentiate between benign pleural effusions and malignant pleural effusions.

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What this paper is about

Objective To investigate the diagnosis value of insulin like growth factor 1(IGF 1) in benign and malignant pleural effusion compared with carcinoembryonic antigen(CEA).Methods IGF 1 and CEA were analyzed by ELISA in 33 cases with benign pleural effusion and 32 cases with malignant pleural effusion.Results The concentration of IGF 1 were significantly higher in malignant pleural effusion(110.20±20.59nmol/L) than that in benign group(76.70±18.95nmol/L),P0.001.IGF 1 was slightly less valuable than CEA in diagnosis of malignant pleural effusion.Conclusion In pleural effusions IGF 1 may be an important indicator to help to differentiate between benign pleural effusions and malignant pleural effusions.

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Available abstract

Objective To investigate the diagnosis value of insulin like growth factor 1(IGF 1) in benign and malignant pleural effusion compared with carcinoembryonic antigen(CEA).Methods IGF 1 and CEA were analyzed by ELISA in 33 cases with benign pleural effusion and 32 cases with malignant pleural effusion.Results The concentration of IGF 1 were significantly higher in malignant pleural effusion(110.20±20.59nmol/L) than that in benign group(76.70±18.95nmol/L),P0.001.IGF 1 was slightly less valuable than CEA in diagnosis of malignant pleural effusion.Conclusion In pleural effusions IGF 1 may be an important indicator to help to differentiate between benign pleural effusions and malignant pleural effusions.

Key concepts: Medicine, Carcinoembryonic antigen, Malignant pleural effusion, Pleural effusion, Effusion, Pathology, Internal medicine, Cancer

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