ScholarLens Back to search
2007•Chinese Journal of Food HygieneRequires access

Virulence Factors of Listeria monocytogenes

Changyun Ye

Open publisher page 0 citations

Abstract

Objective Listeria monocytogenes is a gram-positive,no spore,food-borne pathogen which causes listeriosis.This article reviews the significance of the virulence factors of L.monocytogenes,which are closely related to its pathogenicity.Method Papers relevant to the virulence factors of L.monocytogenes(for example,LLO,PLC,Inl,ActA,P60) were reviewed.Results LLO is a multi-purpose virulence factor and is essential for escaping from the phagocytic vesicle of the macrophage.L.monocytogenes can produce two kinds of PLC:PI-PLC and PC-PLC,which have also evolved for intracellular growth.ActA is required for its unidirectional actin-based motility within an infected host cell.Inl is related to the invasiveness of L.monocytogenes.The P60 protein is the main original antigen of L.monocytogenes.Conclusion A thorough research to the virulence factors will bring about great impact on the treatment and prevention of listeriosis.

About this research paper

What this paper is about

Objective Listeria monocytogenes is a gram-positive,no spore,food-borne pathogen which causes listeriosis.This article reviews the significance of the virulence factors of L.monocytogenes,which are closely related to its pathogenicity.Method Papers relevant to the virulence factors of L.monocytogenes(for example,LLO,PLC,Inl,ActA,P60) were reviewed.Results LLO is a multi-purpose virulence factor and is essential for escaping from the phagocytic vesicle of the macrophage.L.monocytogenes can produce two kinds of PLC:PI-PLC and PC-PLC,which have also evolved for intracellular growth.ActA is required for its unidirectional actin-based motility within an infected host cell.Inl is related to the invasiveness of L.monocytogenes.The P60 protein is the main original antigen of L.monocytogenes.Conclusion A thorough research to the virulence factors will bring about great impact on the treatment and prevention of listeriosis.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective Listeria monocytogenes is a gram-positive,no spore,food-borne pathogen which causes listeriosis.This article reviews the significance of the virulence factors of L.monocytogenes,which are closely related to its pathogenicity.Method Papers relevant to the virulence factors of L.monocytogenes(for example,LLO,PLC,Inl,ActA,P60) were reviewed.Results LLO is a multi-purpose virulence factor and is essential for escaping from the phagocytic vesicle of the macrophage.L.monocytogenes can produce two kinds of PLC:PI-PLC and PC-PLC,which have also evolved for intracellular growth.ActA is required for its unidirectional actin-based motility within an infected host cell.Inl is related to the invasiveness of L.monocytogenes.The P60 protein is the main original antigen of L.monocytogenes.Conclusion A thorough research to the virulence factors will bring about great impact on the treatment and prevention of listeriosis.

Key concepts: Listeria monocytogenes, Virulence, Microbiology, Virulence factor, Listeriolysin O, Biology, Pathogen, Intracellular parasite

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Virulence Factors of Listeria monocytogenes — Research Paper | ScholarLens