Study on the Extraction Technology of Baicalin from Scutellaria baicalensis Georgi

Objective To investigate the best extracting technology of baicalin from Scutellaria baicalensis Georgi.Methods The best extraction method was selected from controlled temperature water immersing,decoction and controlled temperature alkali added water immersing method,and the affecting factors on yield and content of baicalin were investigated.Results The decoction method was better than others,the good technology conditions were as follows:decocted the Scutellaria baicalensis 2 times with decuple water in 60 min and 5 folds water 30 min,respectively,then removed the residue with double filtration cloth and centrifuged,kept the temperature at 70℃ for 60 min,laid aside 3 hours,separated with centrifuge,dried the residue and obtained the baicalin product.The yield and content of baicalin was 13.67% and 85.7% respectively,the baicalin was stable at pH 3.98.Conclusion The results provide a theoretical basis for large-scale prodution of baicalin.