Change of endothelium-dependent dilatation function of brachial artery in young long-term smokers,
Xing Ai-hon, Jiang Zhi-min, Liu Jun-shen
Abstract
Xing Ai-hon, Jiang Zhi-min, Liu Jun-shen
Abstract
Objective: To study the change of endothelium-dcpendent dilatation function of brachia! artery in young long term smokers. Methods: The internal diameters of brachial arteries of flow-mediate (FMD) and glyceryl trinitrate-induced (GTN-induced) were measured in 20 cases young long-term smokers and 15 controls (no smoking). Results: The basic internal diameter of brachial artery and GTN-induced dilatation of brachial artery had no difference (P0. 05) while FMD dilatation had significantly difference [ (3. 61±2.90)% : (8. 32 + 4. 75)%] ( P0. 01). Endothelium-dependent dilatation of brachial artery was negatively associated with quantity of cigarette. Conclusion: The function of endotheiium-dependent dilatation of brachial artery in young long-term smokers is significantly damaged and their damage degree is significantly correlation with quantity of cigarette.
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Objective: To study the change of endothelium-dcpendent dilatation function of brachia! artery in young long term smokers. Methods: The internal diameters of brachial arteries of flow-mediate (FMD) and glyceryl trinitrate-induced (GTN-induced) were measured in 20 cases young long-term smokers and 15 controls (no smoking). Results: The basic internal diameter of brachial artery and GTN-induced dilatation of brachial artery had no difference (P0. 05) while FMD dilatation had significantly difference [ (3. 61±2.90)% : (8. 32 + 4. 75)%] ( P0. 01). Endothelium-dependent dilatation of brachial artery was negatively associated with quantity of cigarette. Conclusion: The function of endotheiium-dependent dilatation of brachial artery in young long-term smokers is significantly damaged and their damage degree is significantly correlation with quantity of cigarette.
Key concepts: Brachial artery, Medicine, Cardiology, Internal medicine, Endothelium, Artery, Blood pressure