2002•Zhongguo yaofangRequires access

Clinical Evaluation of the Efficacy of Azithromycin vs Erythromycin in the Treatment of Acute Infections

Xu Guang, Mao Boqin

Abstract

OBJECTIVE:To evaluation of the efficacy and safety of azithromycin in the treatment of acute infections METHODS:A randomized controlled multicenter clinical study was used to compare the clinical efficacy of azithromycin(200mg q d for 3～5 days) with erythromycin(500mg b i d for 5 days) RESULTS:The cure rate,effective rate,and bacterial clearance rate were 76 7%,95 0%,and 94 3% respectively for azithromycin group and were 48 3%,76 7%,and 77 4% respectively for erythromycin group with a side-effect incidence of 10 0% for azithromycin group and 39 3% for erythromycin group CONCLUSION:Azithromycin is superior to erythromycin in clinical efficacy,safety and side-effect incidence

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Available abstract

Key concepts: Azithromycin, Erythromycin, Medicine, Internal medicine, Clinical efficacy, Incidence (geometry), Cure rate, Antibiotics