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Clinical Research of ~(31)P-MRS for Skeletal Muscle

Qi Jing

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Abstract

As one type of Magnetic Resonance Spectroscopy(MRS),Phosphorus MR spectroscopy(31P-MRS) has special effect in the analysis of energy metabolism of human tissue and cell in vivo,it can quantitatively analyse of the concentrations of inorganic phosphate(Pi),phosphocreatine(PCr),adenosine triphosphate(ATP) and so on.so it plays an important role in the study of skeletal muscle and energy metabolism.Dynamic 31P-MRS technique can survey the change of high energy phosphate compounds in muscle cells during resting state,during and after exercise,evaluate energy conversion efficiency during mucle contraction.This paper reviewed the research of mucle 31P-MRS,particularly focused on the application of the dynamic 31P-MRS.It will lay a good foundation for using the 31P-MRS to study the diseases related to muscles.

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What this paper is about

As one type of Magnetic Resonance Spectroscopy(MRS),Phosphorus MR spectroscopy(31P-MRS) has special effect in the analysis of energy metabolism of human tissue and cell in vivo,it can quantitatively analyse of the concentrations of inorganic phosphate(Pi),phosphocreatine(PCr),adenosine triphosphate(ATP) and so on.so it plays an important role in the study of skeletal muscle and energy metabolism.Dynamic 31P-MRS technique can survey the change of high energy phosphate compounds in muscle cells during resting state,during and after exercise,evaluate energy conversion efficiency during mucle contraction.This paper reviewed the research of mucle 31P-MRS,particularly focused on the application of the dynamic 31P-MRS.It will lay a good foundation for using the 31P-MRS to study the diseases related to muscles.

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Available abstract

As one type of Magnetic Resonance Spectroscopy(MRS),Phosphorus MR spectroscopy(31P-MRS) has special effect in the analysis of energy metabolism of human tissue and cell in vivo,it can quantitatively analyse of the concentrations of inorganic phosphate(Pi),phosphocreatine(PCr),adenosine triphosphate(ATP) and so on.so it plays an important role in the study of skeletal muscle and energy metabolism.Dynamic 31P-MRS technique can survey the change of high energy phosphate compounds in muscle cells during resting state,during and after exercise,evaluate energy conversion efficiency during mucle contraction.This paper reviewed the research of mucle 31P-MRS,particularly focused on the application of the dynamic 31P-MRS.It will lay a good foundation for using the 31P-MRS to study the diseases related to muscles.

Key concepts: Phosphocreatine, Inorganic phosphate, Skeletal muscle, Energy metabolism, Phosphate, High-energy phosphate, Adenosine triphosphate, Chemistry

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