2004•Qilu yixue zazhiRequires access
Relationship between oocyte morphology based on first polar body, perivitelliine space and cytoplasm and the outcome after intracytoplasmic sperm injection
Shuhua Zou, Fenglan Li, Rui-Ying Wu, Xiaoyan Wang, Bi Yuan, Haitao Wang, Quan Zhang, Yuhong Jiang
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Abstract
Objective A comprehensive study was made in terms of first polar body, perivitelline space and cytoplasm to evaluate the influence of intracytoplasmic sperm injection on the implantation rate and pregnancy so as to provide the evidence of selecting quality embryos for implantation. Methods Oocyte morphology at metaphase Ⅱ(MⅡ) was evaluated based on first polar body, perivitelline space and cytoplasm. MⅡ oocytes were graded into five groups. The implantation rate and clinical pregnancy rate were compared between the groups. Results The implantation rate and clinical pregnancy rate of embryos which developed from all gradeⅠoocytes were significantly higher than those from at least one gradeⅠoocyte(χ 2=4.29,5.40;P0.05). The implantation rate and clinical pregnancy rate of embryos which developed from at least one gradeⅠoocyte were significantly higher than those from all oocytes with abnormal morphology (χ 2=11.22,15.10; P0.01). Conclusion Human oocytes grading based on first polar body, perivitelline space and cytoplasmic morphology is effective to increase the implantation rate and pregnancy rate.