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2006•Zhongguo aizheng zazhiRequires access

Diagnosis and treatment of gestational trophoblastic neoplasia

Xing Xie

Open publisher page 1 citations

Abstract

Gestational trophoblastic neoplasia (GTN) includes invasive mole and choriocarcinoma. Before the discovery of effective chemotherapeutic agents for human chorionic gonadotropin (HCG), the survival prognosis for the patients with the disease was very poor. At present, with the setup of sensitive quantitative assays and new drugs to be developed for HCG, most women with GTN can be cured and their reproductive function preserved. The purpose of this paper is to address current opinions regarding the diagnosis, staging, and management of GTN.

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What this paper is about

Gestational trophoblastic neoplasia (GTN) includes invasive mole and choriocarcinoma. Before the discovery of effective chemotherapeutic agents for human chorionic gonadotropin (HCG), the survival prognosis for the patients with the disease was very poor. At present, with the setup of sensitive quantitative assays and new drugs to be developed for HCG, most women with GTN can be cured and their reproductive function preserved. The purpose of this paper is to address current opinions regarding the diagnosis, staging, and management of GTN.

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Available abstract

Gestational trophoblastic neoplasia (GTN) includes invasive mole and choriocarcinoma. Before the discovery of effective chemotherapeutic agents for human chorionic gonadotropin (HCG), the survival prognosis for the patients with the disease was very poor. At present, with the setup of sensitive quantitative assays and new drugs to be developed for HCG, most women with GTN can be cured and their reproductive function preserved. The purpose of this paper is to address current opinions regarding the diagnosis, staging, and management of GTN.

Key concepts: Gestational trophoblastic neoplasia, Choriocarcinoma, Human chorionic gonadotropin, Gestational trophoblastic disease, Medicine, Trophoblastic neoplasm, Placental site trophoblastic tumor, Gynecology

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