Diagnostic meaning of stomach bile reflux monitoring of primary bile reflux gastritis with gastric mucosal lesions

Objective To study the diagnostic meaning of stomach bile reflux monitoring of the primary bile reflux gastritis with gastric mucosal lesions.Methods By endoscopy and 24-hour gastric pH and bilirubin monitoring with Bilitec 2000,the patients of primary bile reflux gastritis with pathologic bile reflux were divided into two groups: with mucosal lesions and without mucosal lesions.Results Between the two groups there were significant differences in the time of long term of reflux in meals(1.3±0.1) times vs(0.6±0.3) times,the maximal term of reflux(268.3±43.7) min vs(151.4±27.7) min,the maximal term of reflux in meal(8.6±2.3) min vs(4.3±1.5) min and after meals(38.9±11.3) min vs(17±7.1) min and the total time of bilirubin absorption value0.14 in meals(16.4±7.5) min vs(9.0±3.6) min.The differences between all indexes of gastric pH in two groups was not significant.Conclusion In the primary bile reflux gastritis,the bile reflux could induce gastric mucosal lesions;monitoring of bile reflux conduces to find out the relativity between the degree or state of gastric bile reflux and gastric mucosal lesion.