Fabrication of Molecularly Imprinted Electrochemical Sensor for the Determination of Nicotinamide in Beverage

In this study,a sensitive sensor based on molecularly imprinted polymer(MIP) of o-phenylenediamine as a functional monomer was designed,and its configuration and performance were explored.The progress of the electropolymerization was performed in an acetate buffer solution(pH 5.7) containing 1.0 mmol/L nicotinamide and 3.0 mmol/L o-phenylenediamine on the surface of a glassy carbon electrode.The molecularly imprinted polymer membrane was characterized using cyclic voltammetry(CV).The linear range was 1.0 × 10-8 ~ 1.0 × 10-6 μmol/L and limit of detection was 4.5 × 10-9 mol/L.The sensor was sensitive,selective,easy to use and cheap and could be applied to the determination of trace nicotinamide in beverage.