The relationship between mutation of the 13 inverted sequence in the mtrR promoter region of neisseria gonorrhoeae and tis resistance of tritonX-100
Li Han
Abstract
Li Han
Abstract
Objective:To study the relationship between mutation of the13inverted sequence in the mtrR promoter region of neisseria gonˉorrhoeae and its resistance of tritonX-100.Methods:The MIC of tritonX-100was determined and13inverted sequence was amplified by polymerase chain reaction(PCR).Five strains were choosen at random to sequenced.Results:All five strains produced single-base deleˉtion.Conclusion:The single-base deletion of the13inverted sequence in the mtrR promoter region of neisseria gonorrhoeae may trigger the reˉsistance enhancing of neisseria gonorrhoeae against tritonX-100.
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Objective:To study the relationship between mutation of the13inverted sequence in the mtrR promoter region of neisseria gonˉorrhoeae and its resistance of tritonX-100.Methods:The MIC of tritonX-100was determined and13inverted sequence was amplified by polymerase chain reaction(PCR).Five strains were choosen at random to sequenced.Results:All five strains produced single-base deleˉtion.Conclusion:The single-base deletion of the13inverted sequence in the mtrR promoter region of neisseria gonorrhoeae may trigger the reˉsistance enhancing of neisseria gonorrhoeae against tritonX-100.
Key concepts: MTRR, Neisseria gonorrhoeae, Neisseria, Mutation, Medicine, Genetics, Sequence (biology), Microbiology