2006Radiologic PracticeRequires access

Diagnostic Value of MRI in Early Uterus Cervical Cancer

Xiaolin Zheng

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Abstract

Objectives:To evaluate the diagnostic value of MRI in stage Ⅰ~Ⅱuterus cervical cancer and the role of pre-surgery staging.Methods:In 50 patients with surgery and pathology proved uterus cervical carcinoma,their clinical(material) and MRI findings were retrospectively analyzed.The size,location,signal intensity and extent of tumor were studied.The MR sequences included SE T_1WI,TSE T_2WI,T_2WI-SPIR and contrast enhanced T_1WI.Results:Apart from 2 patients with stage Ⅰa,48 patients having uterus cervical carcinoma were detected by MRI,showing hypo-intensity and/or iso-intensity on T_1WI,heterogeneous and homogeneous hyper-intensity on T_2WI,mild homogeneous/heterogeneous enhancement after intravenous bolus administration of Gd-DTPA.The accuracy of MRI in the localization of tumor was 96%.In 40 patients,MRI showed a 62.5% consistency when compared with pathology staging.For the staging of carcinoma of(uterine) cervix,the accuracy of MRI was 81.2%,compared with that of physical examination(62.5%),statistically dif-(ference) existed(χ~2=4.17,P0.05).The tumor size measured by MRI was(1.94±1.15)cm,compared with that measured by pathology specimen(1.94±1.11)cm,no(P0.05).Conclusion:The staging,including tumor size and extent assessment of uterus cervical cancer,could be accurately evaluated by MRI,which is superior to that of physical examination before surgery.Yet,the value of MRI is limited in stage Ia carcinoma,study combined with clinical material and cytology(findings) is mandated.

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Objectives:To evaluate the diagnostic value of MRI in stage Ⅰ~Ⅱuterus cervical cancer and the role of pre-surgery staging.Methods:In 50 patients with surgery and pathology proved uterus cervical carcinoma,their clinical(material) and MRI findings were retrospectively analyzed.The size,location,signal intensity and extent of tumor were studied.The MR sequences included SE T_1WI,TSE T_2WI,T_2WI-SPIR and contrast enhanced T_1WI.Results:Apart from 2 patients with stage Ⅰa,48 patients having uterus cervical carcinoma were detected by MRI,showing hypo-intensity and/or iso-intensity on T_1WI,heterogeneous and homogeneous hyper-intensity on T_2WI,mild homogeneous/heterogeneous enhancement after intravenous bolus administration of Gd-DTPA.The accuracy of MRI in the localization of tumor was 96%.In 40 patients,MRI showed a 62.5% consistency when compared with pathology staging.For the staging of carcinoma of(uterine) cervix,the accuracy of MRI was 81.2%,compared with that of physical examination(62.5%),statistically dif-(ference) existed(χ~2=4.17,P0.05).The tumor size measured by MRI was(1.94±1.15)cm,compared with that measured by pathology specimen(1.94±1.11)cm,no(P0.05).Conclusion:The staging,including tumor size and extent assessment of uterus cervical cancer,could be accurately evaluated by MRI,which is superior to that of physical examination before surgery.Yet,the value of MRI is limited in stage Ia carcinoma,study combined with clinical material and cytology(findings) is mandated.

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Available abstract

Objectives:To evaluate the diagnostic value of MRI in stage Ⅰ~Ⅱuterus cervical cancer and the role of pre-surgery staging.Methods:In 50 patients with surgery and pathology proved uterus cervical carcinoma,their clinical(material) and MRI findings were retrospectively analyzed.The size,location,signal intensity and extent of tumor were studied.The MR sequences included SE T_1WI,TSE T_2WI,T_2WI-SPIR and contrast enhanced T_1WI.Results:Apart from 2 patients with stage Ⅰa,48 patients having uterus cervical carcinoma were detected by MRI,showing hypo-intensity and/or iso-intensity on T_1WI,heterogeneous and homogeneous hyper-intensity on T_2WI,mild homogeneous/heterogeneous enhancement after intravenous bolus administration of Gd-DTPA.The accuracy of MRI in the localization of tumor was 96%.In 40 patients,MRI showed a 62.5% consistency when compared with pathology staging.For the staging of carcinoma of(uterine) cervix,the accuracy of MRI was 81.2%,compared with that of physical examination(62.5%),statistically dif-(ference) existed(χ~2=4.17,P0.05).The tumor size measured by MRI was(1.94±1.15)cm,compared with that measured by pathology specimen(1.94±1.11)cm,no(P0.05).Conclusion:The staging,including tumor size and extent assessment of uterus cervical cancer,could be accurately evaluated by MRI,which is superior to that of physical examination before surgery.Yet,the value of MRI is limited in stage Ia carcinoma,study combined with clinical material and cytology(findings) is mandated.

Key concepts: Medicine, Stage (stratigraphy), Cervical cancer, Uterus, Magnetic resonance imaging, Radiology, Cervical carcinoma, Carcinoma

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