Clinical efficacy of continuous venous-venous hemofiltration combined with hemoperfusion for patients with multiple organ dysfunction syndrome

Objective:To evaluate the effect of continuous venous-venous hemofiltration combined with hemoperfusion for patients with multiple organ dysfunction syndrome.Methods:37 cases with multiple organ dysfunction syndrome in our hospital from January 2009 to December 2010 were treated by continuous venous-venous hemofiltration and hemoperfusion.Results:After treatment,BT,BR,HR,MAP,Na+,K+,BUN,Scr,IL-8,TNF-α of the patients were(36.9±0.4)℃,(25.1±4.6) time/min,(95.6±14.2) time/min,(85.7±7.5) mm Hg,(132.2±8.8) mmol/L,(4.06±0.68) mmol/L,(19.1±5.2) mmol/L,(386.4±132.7) μmol/L,(31.9±7.3) ng/L and(46.4±6.8) ng/L,respectively.And they were much better than those before treatment,there were significant differences(all P0.05).Conclusion:Continuous venous-venous hemofiltration combined with hemoperfusion can relieve the clinical symptom,improve the organ function of patients with multiple organ dysfunction syndrome,and no obviously adverse effect happened.It's an ideal method for MODS.