ScholarLens Back to search
2010•Chinese Journal of Health Laboratory TechnologyRequires access

Determination of melamine in raw milk and dariy products by UPLC-ESI-MS/MS

Hang Yuan-yuan

Open publisher page 0 citations

Abstract

Objective:A UPLC-ESI-MS/MS method was developed for the determination of melamine in raw milk and dairy products.Methods: Sample was extracted and purified by SPE Oasis MCX.After centrifugation,melamine was determined by UPLC-ESI(+)-MS/MS and quantified with multiple reaction monitoring(MRM) mode.Results: The detection limit(LOD) for melamine was 1.0 μg/kg.The limit of quantification(LOQ) was 5.0 μg/kg.The linear range was from 0.5 to 100 μg/L with correlation coefficients above 0.9995.The mean recoveries were between 89% and 104%.Conclusion: This method can be applied for the determination of melamine in raw milk and dairy products for its high sensitivity and high selectivity.

About this research paper

What this paper is about

Objective:A UPLC-ESI-MS/MS method was developed for the determination of melamine in raw milk and dairy products.Methods: Sample was extracted and purified by SPE Oasis MCX.After centrifugation,melamine was determined by UPLC-ESI(+)-MS/MS and quantified with multiple reaction monitoring(MRM) mode.Results: The detection limit(LOD) for melamine was 1.0 μg/kg.The limit of quantification(LOQ) was 5.0 μg/kg.The linear range was from 0.5 to 100 μg/L with correlation coefficients above 0.9995.The mean recoveries were between 89% and 104%.Conclusion: This method can be applied for the determination of melamine in raw milk and dairy products for its high sensitivity and high selectivity.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:A UPLC-ESI-MS/MS method was developed for the determination of melamine in raw milk and dairy products.Methods: Sample was extracted and purified by SPE Oasis MCX.After centrifugation,melamine was determined by UPLC-ESI(+)-MS/MS and quantified with multiple reaction monitoring(MRM) mode.Results: The detection limit(LOD) for melamine was 1.0 μg/kg.The limit of quantification(LOQ) was 5.0 μg/kg.The linear range was from 0.5 to 100 μg/L with correlation coefficients above 0.9995.The mean recoveries were between 89% and 104%.Conclusion: This method can be applied for the determination of melamine in raw milk and dairy products for its high sensitivity and high selectivity.

Key concepts: Melamine, Chemistry, Chromatography, Detection limit, Raw milk, Selected reaction monitoring, Linear correlation, Linear range

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of melamine in raw milk and dariy products by UPLC-ESI-MS/MS — Research Paper | ScholarLens