2006Medical Laboratory SciencesRequires access

Evaluating the risk of coronary heart disease with the co-detection of high-sensitivity C-RP and lipid

Sun Guanzhong

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Abstract

Objective To investigate the value of high-sensitivity serum C-reaction protein(hsCRP)and lipid for evaluating the risk of coronary heart disease(CHD).Methods Serum hsCRP and lipid were detected from 397 positive patients by coronary artery angiography,23 patients with myocardial infarction and 375 healthy volunteers.The risk coefficient(RC)of CHD patients and controls,and those between male and female patients were analyzed statistically.Results There were significant differences in respects of serum lipid,hsCRP and the risk coefficient among different age teams(except 30-39 and 40-49 year teams).The risk coefficient of the patients with CHD were much higher than that of controls.There were not significant differences of the risk coefficient among the CHD positive teams.Conclusions Advanced evaluating standard of the risk coefficient based on evaluating the CHD risk with hsCRP and lipid.The risk coefficient combines the intrinsic factors of atherosis,namely plasma lipoprotein and hsCRP.It can sufficiently reflect the clinical varieties of atherosis in theory,and incarnate the risk of CHD.It eliminates sex difference of the lab data in evaluating the CHD risk,so is more valuable in clinic.

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Objective To investigate the value of high-sensitivity serum C-reaction protein(hsCRP)and lipid for evaluating the risk of coronary heart disease(CHD).Methods Serum hsCRP and lipid were detected from 397 positive patients by coronary artery angiography,23 patients with myocardial infarction and 375 healthy volunteers.The risk coefficient(RC)of CHD patients and controls,and those between male and female patients were analyzed statistically.Results There were significant differences in respects of serum lipid,hsCRP and the risk coefficient among different age teams(except 30-39 and 40-49 year teams).The risk coefficient of the patients with CHD were much higher than that of controls.There were not significant differences of the risk coefficient among the CHD positive teams.Conclusions Advanced evaluating standard of the risk coefficient based on evaluating the CHD risk with hsCRP and lipid.The risk coefficient combines the intrinsic factors of atherosis,namely plasma lipoprotein and hsCRP.It can sufficiently reflect the clinical varieties of atherosis in theory,and incarnate the risk of CHD.It eliminates sex difference of the lab data in evaluating the CHD risk,so is more valuable in clinic.

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Available abstract

Objective To investigate the value of high-sensitivity serum C-reaction protein(hsCRP)and lipid for evaluating the risk of coronary heart disease(CHD).Methods Serum hsCRP and lipid were detected from 397 positive patients by coronary artery angiography,23 patients with myocardial infarction and 375 healthy volunteers.The risk coefficient(RC)of CHD patients and controls,and those between male and female patients were analyzed statistically.Results There were significant differences in respects of serum lipid,hsCRP and the risk coefficient among different age teams(except 30-39 and 40-49 year teams).The risk coefficient of the patients with CHD were much higher than that of controls.There were not significant differences of the risk coefficient among the CHD positive teams.Conclusions Advanced evaluating standard of the risk coefficient based on evaluating the CHD risk with hsCRP and lipid.The risk coefficient combines the intrinsic factors of atherosis,namely plasma lipoprotein and hsCRP.It can sufficiently reflect the clinical varieties of atherosis in theory,and incarnate the risk of CHD.It eliminates sex difference of the lab data in evaluating the CHD risk,so is more valuable in clinic.

Key concepts: Medicine, Coronary heart disease, Internal medicine, Myocardial infarction, Cardiology, Risk factor, Coronary angiography, Coronary artery disease

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