2008•Zhongguo yixue yingxiang jishuRequires access

Analytic methods on functional connectivity based on resting-state fMRI and their applications

Chunshui Yu

Abstract

Most of functional magnetic resonance imaging(fMRI)studies have employed task-related paradigm to explore brain response to an external stimulus.However,the brain is very active in the absence of any specific experimental tasks and the spontaneous activity exhibits coherent low-frequency synchrony.Studies on resting-state brain activity have provided insight into the intrinsic activity mechanism of the brain.In this study we review recent popular methods on resting-state functional connectivity and their preliminary applications to clinical diseases.

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Available abstract

Key concepts: Resting state fMRI, Functional magnetic resonance imaging, Medicine, Functional connectivity, Brain activity and meditation, Neuroscience, Stimulus (psychology), Mechanism (biology)