Effects of Volatile Oil of Jingfukang Granule on Thrombosis,Blood Viscosity and Cerebral Blood Flow

Objective:To study the effects of volatile oil of Jingfukang granule(VOJFKG) on thrombosis,blood viscosity,cerebral blood flow(CBF) and cerebral vascular resistance(CVR).Method:The vitro thrombus was induced and the length,wet and dry weight of the thrombus were measured.Thrombosis instrument was used to observe the in vivo occlusion time(OT).At the same time,the platelet aggregation rate,the high-,middle-,low-shear blood viscosity as well as the plasma viscosity in rats were determined.The CBF and CVR were measured before and after drugs in dogs.Result:VOJFKG can delay the OT,decrease the length,wet and dry weight of in vitro thrombus and the platelet aggregation rate,reduce the blood viscosity,increase CBF.Conclusion:VOJFKG can significantly promote blood circulation and remove blood stasis,andimprove the head blood-supply insufficiency.