Effects of Fentanyl on Pain Caused by Propofol Injection and Induced Abortion

Objective:To assess the effect of fentanyl and lidocaine on propofol-induced injection pain and vacuum abortion-induced pain.Method: 90 ASA grade I-II women scheduled for ambulatory pregnancy termination were randomly divided into three groups: The control group(n=30) received normal saline 2 ml before propofol injection;Lidocaine group(n=30) received 1% lidocaine 2 ml before propofol injection;Fentanyl group(n=30) received 25μg/ml fentanyl 2 ml before propofol injection.Pain at the time of propofol injection was assessed using a four-point verbal rating scale.The number of writhes during the operation and the recovery time of consciousness were recorded.Result:The propofol injection pain in fentanyl group was similar to that in lidocaine group,and the propofol injection pain in fentanyl group and lidocaine group were less than those in control group(P0.01).The number of writhes in fentanyl group were fewer than those in lidocaine group and control group(P0.05),and the number of writhes in lidocaine group were similar to those in control group.The recovery time of consciousness in three groups were similar.All patients left hospital safely in 30 minutes.Conclusion: Fentanyl and lidocaine can effectively reduce the propofol injection pain,and fentanyl can decrease the vacuum abortion-induced pain.Propofol plus small doses fentanyl as general anesthetics for early termination pregnancy is a safe method.