Effect of two cycloplegics on aberration measurements

Objective To study the effects of cyclopentolate and tropicamide on aberration measurements. Methods The patients were divided randomly into cyclopentolate group (15 cases,30 eyes) and tropicamide group (15 cases,29 eyes) . Wavefront aberrations were measured in dark and measured again with mydriatics. Wavefront sphere (6 mm) and high-order aberrations were compared before and after dilation in both groups. Results The wavefront sphere in dark was more negative than Optometry sphere and wavefront sphere after dilation (P 0. 05) . In both groups, there were significant differences on high-order aberrations (RMS3,RMS4,RMS5,RMSh) and spherical aberration (P 0.05) ,and no significant differences on the coma (P 0.05) in different analyzing pupil diameter. There were no significant differences on high-order aberrations and coma between scotopic and dilated conditions (P 0. 05) . And the spherical aberration after dilated increased statistically in both two groups (P 0. 05) . But there was no significant difference between two groups on spherical aberration in scotopic condition (P 0. 05) . Conclusions The mydriatics could affect the measurement of aberration,especially the spherical aberration.