The effects of Stellera chamaejasme on superoxide dismutase,glutathione peroxidase and malondialdehyde in the tissues of white mice

To observe the effects of Stellera chamaejasme on superoxide dismutase( SOD),glutathione peroxidase( GSH- Px),and malondialdehyde( MDA) in various tissues of white mice,40 white mice were divided into 2 groups,and the mice each were drenched with 0. 25 ml 1% decoction of Stellera chamaejasme and 0. 25 mL 0. 9% normal saline,respectively. All the mice were decapitated and removed the tissues and organs concerned after 40 d,including heart,liver,spleen,lung,and kidney,which were used to determine SOD,GSH- Px,MDA,and other indicators. The results showed that Stellera chamaejasme could improve SOD,GSH- Px activity in the heart,liver,spleen,lung,and kidney, in which the GSH- Px activity was significantly increased( P 0. 05) in the spleen,lung,kidney; the contents of MDA were reduced in the heart,liver,spleen,lung,and kidney,in which the contents of MDA were significantly lower( P 0. 05) in the liver,lung and kidney. The results indicate that Stellera chamaejasme has a role to improve the anti- oxidant and anti- aging abilities in white mice.