Postantibiotic Effect of Galla chinensis on Pathogenic Bacteria of Eels in vitro

The postantibiotic effect(PAE) of Galla chinensis on cardinal pathogenic bacteria of eels including of Enterobacter B01,Edwardsiella tarda B09,Aeromonas caviae B18,Aeromonas hydrophila B27 in vitro were determined in this study.Dilution method was used for the drug of Galla chinensis removal and Mueller-Hinton agar colony counting method was used to monitored the growth of bacteria.The results showed that marked PAE was found even in the subinhibitory concentration(sub-MIC) when Galla chinensis were used against four common pathogenic bacteria of eels and the isolate obtained from veterinary clinic at concentration of 0.25,0.5,1,2 and 4 times of MIC.The duration of PAE was enhanced with the increasing concentration,showing strongly a concentration dependent,especially at 4 times of MIC,the PAE was obvirously prolonged(P0.05).It suggested that longer dosing interval should be recommended when the Galla chinensis drug used against eels pathogenic bacteria,which achieved reducing side-effect against eels and reversely working on growth of eels.