Protective Effect of Intracord Transplantion of Neurvl Stem Cells on Spinal Cord Injury

Objective To Study the protective effects of intracord transplantataion of human Neural Stem Cells on spinal cord injury(SCI). Methods Neurae Stem Cells (NSCs) were divived from human fetal hippocampi, Rats with semi-division (SD) of spinal cord was divided into 3 groups. Group A consisted of the rats with SD treated with the transplantation of NSCs, group B of the rat with SD without treatment and group C was the normal control, 24h after operation, 8 rats of each group were Killed and the injured segment of the spinal cord was resected to be examined with neurological furction test and MEP monitoring. Results There was a significant increase of water contant and Na+?Ca2+ ions and decrease K+?Mg2+ ions in the injured Cord segment of group B and a statistically significant recovery was observed in group A. The intracord transplantation of NSCs improved the nerological outcome of injured spinal cord. Conclusions The intracord transplantation of NSCs exerts protective effects on injured segment of spinal cord through the improvement of the internal ion environment of spinal cord.