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Supercritical Fluid-Simulated Moving Bed Chromatography and Applications

Bin Chen

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Abstract

By applying supercritical fluid to simulated moving bed chromatography as eluent,thus a new separating method is developed :supercritical fluid-simulated moving bed chromatography,which accumulates the superiority of both SFC and SMB,furthermore,the operating difficulty of SMB in pressure gradient is overcomed,the application field and production scale of SFC is widened.In this paper the development,theory fundament,operating mode and its application is reviewed.

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What this paper is about

By applying supercritical fluid to simulated moving bed chromatography as eluent,thus a new separating method is developed :supercritical fluid-simulated moving bed chromatography,which accumulates the superiority of both SFC and SMB,furthermore,the operating difficulty of SMB in pressure gradient is overcomed,the application field and production scale of SFC is widened.In this paper the development,theory fundament,operating mode and its application is reviewed.

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Available abstract

By applying supercritical fluid to simulated moving bed chromatography as eluent,thus a new separating method is developed :supercritical fluid-simulated moving bed chromatography,which accumulates the superiority of both SFC and SMB,furthermore,the operating difficulty of SMB in pressure gradient is overcomed,the application field and production scale of SFC is widened.In this paper the development,theory fundament,operating mode and its application is reviewed.

Key concepts: Simulated moving bed, Supercritical fluid chromatography, Supercritical fluid, Chromatography, Column chromatography, Packed bed, Materials science, Chemistry

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